MXene-based electrochemical devices applied for healthcare applications.
Lenka LorencovaPeter KasakNatalia KosutovaMonika JerigovaEva NoskovicovaAlica VikartovskaMarek BarathPavol FarkasJan TkacPublished in: Mikrochimica acta (2024)
The initial part of the review provides an extensive overview about MXenes as novel and exciting 2D nanomaterials describing their basic physico-chemical features, methods of their synthesis, and possible interfacial modifications and techniques, which could be applied to the characterization of MXenes. Unique physico-chemical parameters of MXenes make them attractive for many practical applications, which are shortly discussed. Use of MXenes for healthcare applications is a hot scientific discipline which is discussed in detail. The article focuses on determination of low molecular weight analytes (metabolites), high molecular weight analytes (DNA/RNA and proteins), or even cells, exosomes, and viruses detected using electrochemical sensors and biosensors. Separate chapters are provided to show the potential of MXene-based devices for determination of cancer biomarkers and as wearable sensors and biosensors for monitoring of a wide range of human activities.
Keyphrases
- healthcare
- molecularly imprinted
- ionic liquid
- label free
- solid phase extraction
- gold nanoparticles
- induced apoptosis
- endothelial cells
- papillary thyroid
- mesenchymal stem cells
- low cost
- cell cycle arrest
- stem cells
- electron transfer
- cell free
- circulating tumor
- squamous cell carcinoma
- heart rate
- single molecule
- health information
- oxidative stress
- molecular dynamics simulations
- signaling pathway
- cell death
- young adults
- endoplasmic reticulum stress
- lymph node metastasis
- genetic diversity
- pluripotent stem cells
- mass spectrometry
- social media
- cell proliferation
- simultaneous determination
- tandem mass spectrometry
- health insurance
- climate change
- childhood cancer