Longitudinal Dopamine D2 Receptor Changes and Cerebrovascular Health in Aging.
Nina KaralijaJarkko JohanssonGoran PapenbergAnders WåhlinAlireza SalamiYlva KöhnckeAndreas M BrandmaierMicael AnderssonJan AxelssonKatrine RiklundMartin LövdénUlman LindenbergerLars BäckmanLars NybergPublished in: Neurology (2022)
These findings provide the first longitudinal evidence for individual and region-specific differences of DRD2 decline in older age and support the hypothesis that cerebrovascular factors are linked to age-related dopaminergic decline.