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Familial Cerebellar Ataxia and Amyotrophic Lateral Sclerosis/Frontotemporal Dementia with DAB1 and C9ORF72 Repeat Expansions: An 18-Year Study.

Angela RosenbohmHendrik PottMirja ThomsenHaloom RafehiSabine KayaSilke SzymczakAlexander E VolkKathrin MuellerIsabel SilveiraJochen H WeishauptHolger TönniesPhilip SeiblerKatja ZschiedrichSusen SchaakeAna WestenbergerChristine ZühlkeChristel DepienneJoanne TrinhAlbert C LudolphChristine KleinMelanie BahloKatja Lohmann
Published in: Movement disorders : official journal of the Movement Disorder Society (2022)
We demonstrate genetic and clinical findings during an 18-year period in a unique family carrying two different pathogenic repeat expansions, providing novel insights into their genotypic and phenotypic spectrums. © 2022 The Authors. Movement Disorders published by Wiley Periodicals LLC on behalf of International Parkinson and Movement Disorder Society.
Keyphrases
  • amyotrophic lateral sclerosis
  • early onset
  • affordable care act
  • genome wide
  • randomized controlled trial
  • healthcare
  • gene expression