Impact of Cumulative Inflammation, Cardiac Risk Factors, and Medication Exposure on Coronary Atherosclerosis Progression in Rheumatoid Arthritis.
George Athanasios KarpouzasSarah R OrmsethElizabeth HernandezMatthew J BudoffPublished in: Arthritis & rheumatology (Hoboken, N.J.) (2020)
Inflammation was a consistent and independent predictor of coronary atherosclerosis progression in RA. It should therefore be specifically targeted toward mitigating cardiovascular risk. Biologic disease-modifying antirheumatic drugs, statins, and BP control may further constrain plaque progression directly or indirectly.
Keyphrases
- rheumatoid arthritis
- coronary artery disease
- cardiovascular disease
- risk factors
- disease activity
- oxidative stress
- coronary artery
- ankylosing spondylitis
- interstitial lung disease
- healthcare
- left ventricular
- rheumatoid arthritis patients
- emergency department
- type diabetes
- cancer therapy
- drug delivery
- aortic stenosis
- adverse drug
- aortic valve
- idiopathic pulmonary fibrosis
- atrial fibrillation