Login / Signup

Siponimod (BAF312) penetrates, distributes, and acts in the central nervous system: Preclinical insights.

Marc BigaudBettina RudolphEmmanuelle BriardChristian BeerliAndreas HofmannErwin HermesFlorian MuellershausenAnna SchubartAnne Gardin
Published in: Multiple sclerosis journal - experimental, translational and clinical (2021)
Findings demonstrate siponimod's CNS penetration and distribution across species, with high translational potential to human.
Keyphrases
  • endothelial cells
  • induced pluripotent stem cells
  • blood brain barrier
  • pluripotent stem cells
  • cerebrospinal fluid
  • cell therapy
  • mesenchymal stem cells
  • climate change