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Multi-trait meta-analyses reveal 25 quantitative trait loci for economically important traits in Brown Swiss cattle.

Zih-Hua FangHubert Pausch
Published in: BMC genomics (2019)
Our findings provide a comprehensive overview of QTL segregating in Brown Swiss cattle. Detected QTL explain between 2 and 10% of the variation in the estimated breeding values and thus may be considered as the most important QTL segregating in the Brown Swiss cattle breed. Multi-trait association testing boosts the power to detect pleiotropic QTL and assesses the full spectrum of phenotypes that are affected by trait-associated variants.
Keyphrases
  • genome wide
  • dna methylation
  • copy number
  • high density
  • meta analyses
  • systematic review
  • randomized controlled trial
  • gene expression
  • high resolution
  • single cell
  • mass spectrometry