Cannabis-opioid interaction in the treatment of fibromyalgia pain: an open-label, proof of concept study with randomization between treatment groups: cannabis, oxycodone or cannabis/oxycodone combination-the SPIRAL study.

Cornelis Jan van DamMonique van VelzenCornelis KramersArnt F A SchellekensErik OlofsenMarieke NiestersAlbert Dahan

Published in: Trials (2023)

The trial is designed to determine whether self-titration of oxycodone and cannabis will reduce side effects in chronic pain patients with fibromyalgia. TRIAL REGISTRATION {2A AND 2B}: EU trial register 2019-001861-33, URL https://www.clinicaltrialsregister.eu , on July 17, 2019; World Health Organization International Clinical Trials Research Platform NL7902, URL https://trialsearch.who.int , on July 26, 2019.

Keyphrases

chronic pain
clinical trial
phase iii
phase ii
study protocol
pain management
randomized controlled trial
open label
high throughput
neuropathic pain
combination therapy
spinal cord injury
postoperative pain