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Skull Density Ratio as Arm-Allocation Parameter for a Controlled Focused Ultrasound Trial in Parkinson's Disease.

Jose Angel Pineda-PardoR Martinez FernandezElena Natera-VillalbaAgustina Ruiz-YanziRafael Rodríguez-RojasMarta Del AlamoTamara Jiménez-CastellanosMichele MatarazzoCarmen Gasca-SalasOlivier RascolJosé A Obeso
Published in: Movement disorders clinical practice (2024)
Our results show that in a PD population considered for FUS subthalamotomy treatment, the SDR may be a valid group-allocation parameter. This could be considered as the basis for a controlled study comparing FUS subthalamotomy vs BMT.
Keyphrases
  • clinical trial
  • study protocol
  • phase iii
  • randomized controlled trial
  • combination therapy
  • open label
  • replacement therapy