BRAFV600E mutations and immunohistochemical expression of VE1 protein in low-grade serous neoplasms of the ovary.

Gulisa TurashviliRachel N GrishamSarah ChiangDeborah F DeLairKay J ParkRobert A SoslowRajmohan Murali

Published in: Histopathology (2018)

BRAFV600E mutations are significantly more common in SBTs than in LGSCs. Immunohistochemical expression of VE1 protein is associated strongly with BRAFV600E mutation and BRAF mutation-associated histological features. VE1 immunohistochemistry is a reliable method for the detection of BRAFV600E mutations.

Keyphrases

low grade
high grade
poor prognosis
binding protein
protein protein
long non coding rna
small molecule
loop mediated isothermal amplification
metastatic colorectal cancer
quantum dots