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Brain Metastases from Biliary Tract Cancer: Case Series and Clinicogenomic Analysis.

Grace N DodooBrian Sandeep DeSunyoung S LeeJoseph Abi JaoudeJean-Nicholas VautheyChing-Wei D TzengHop S Tran CaoKalman A KatlowitzJacob J MandelThomas H BeckhamBruce D MinskyGrace L SmithEmma B HollidayAlbert C KoongPrajnan DasCullen M TaniguchiMilind JavleEugene Jon KoayEthan Bernard Ludmir
Published in: The oncologist (2023)
This is the largest series of patients with BrM-BTC to date and provides molecular characterization of this rare subgroup of patients with BTC. Patients with BrM-BTC may be more likely to have BRAF mutations. With advances in targeted therapy for patients with BTC with actionable mutations, continued examination of shifting patterns of failure, with emphasis on BrM, is warranted.
Keyphrases
  • brain metastases
  • small cell lung cancer
  • squamous cell
  • cancer therapy
  • randomized controlled trial
  • clinical trial
  • squamous cell carcinoma
  • young adults
  • phase iii
  • wild type
  • data analysis
  • open label