Anosmia and other SARS-CoV-2 positive test-associated symptoms, across three national, digital surveillance platforms as the COVID-19 pandemic and response unfolded: an observation study.
Carole Helene SudreAyya KeshetMark S GrahamAmit D JoshiSmadar ShiloHagai RossmanBenjamin MurrayErika MolteniKerstin KlaserLiane S CanasMichela AntonelliMarc ModatJoan Capdevila PujolSajaysurya GaneshJonathan WolfTomer MeirAndrew T ChanClaire J StevesTimothy D SpectorJohn S BrownsteinEran SegalSébastien OurselinChristina M AstleyPublished in: medRxiv : the preprint server for health sciences (2020)
The strong association of anosmia/ageusia with self-reported SARS-CoV-2 test positivity is omnipresent, supporting its validity as a reliable COVID-19 signal, regardless of the participatory surveillance platform or testing policy. This analysis highlights that precise effect estimates, as well as an understanding of test access patterns to interpret differences, are best done only when incidence is high. These findings strongly support the need for testing access to be as open as possible both for real-time epidemiologic investigation and public health utility.