Chronic venous disease patients show increased IRS-4 expression in the great saphenous vein wall.
Miguel Ángel OrtegaOscar Fraile-MartínezCielo García-MonteroFernando Ruiz-GrandeSilvestra Barrena-BlázquezHector MontoyaLeonel PekarekSofia ZoullasMiguel A Alvarez-MonFelipe SainzAngel AsúnsoloJulio AceroMelchor Álvarez-MonJulia BujánNatalio García-HonduvillaLuis G GuijarroPublished in: The Journal of international medical research (2021)
IRS-4 may be implicated in CVeD development and progression. Therefore, IRS-4 could be a potential diagnostic or therapeutic target for patients with this condition.