Smoking intensity and bladder cancer aggressiveness at diagnosis.
André L A BarbosaSita H H M VermeulenKatja K AbenAnne J GrotenhuisAlina VrielingLambertus A L M KiemeneyPublished in: PloS one (2018)
We observed a weak increase in the risk of a more aggressive tumor type with increasing smoking intensity in former smokers, but this association was absent in current smokers. This conflicting result may suggest that there is no strong relation between smoking intensity and bladder cancer aggressiveness. Analyses of prospective studies with longitudinal smoking assessment may provide a more definitive answer to the research question.