Randomized prospective trial of fractionated stereotactic radiosurgery with chemotherapy versus chemotherapy alone for bevacizumab-resistant high-grade glioma.
David BergmanAnkit ModhLonni SchultzJames SnyderTom MikkelsenMira ShahSamuel RyuM Salim SiddiquiTobias WalbertPublished in: Journal of neuro-oncology (2020)
FSRS combined with BEV-based chemotherapy in recurrent HGG patients progressing on BEV is feasible and improves LC and PFS when compared to treatment with BEV-based chemotherapy alone.
Keyphrases
- locally advanced
- high grade
- end stage renal disease
- phase iii
- chronic kidney disease
- newly diagnosed
- ejection fraction
- clinical trial
- squamous cell carcinoma
- open label
- phase ii
- chemotherapy induced
- rectal cancer
- randomized controlled trial
- study protocol
- radiation therapy
- small cell lung cancer
- mass spectrometry
- placebo controlled
- simultaneous determination