Chemically defined human vascular laminins for biologically relevant culture of hiPSC-derived brain microvascular endothelial cells.
Pedram MotallebnejadSamira M AzarinPublished in: Fluids and barriers of the CNS (2020)
LN 511 improves the functionality and long-term barrier stability of iBMECs. Our findings suggest that incorporation of physiologically relevant LN 511 in iBMEC culture would be beneficial for disease modeling applications and BBB-on-a-chip platforms that accommodate fluid flow.