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Characterization of the immune microenvironment in brain metastases from different solid tumors.

Jinling JiangLihong WuFei YuanJun JiXiaojing LinWanning YangJunwei WuMin ShiHui YangYanna MaXue SongZhenggang ZhuHenghui ZhangJun Zhang
Published in: Cancer medicine (2020)
This study presents an immune landscape of brain metastases from different cancer types. With high RNA expression levels of PD-1/PD-L1 axis and immune infiltration in brain metastases, it would be worthwhile to explore the efficacy of immune checkpoint blockade for lung cancer patients with intracranial metastases.
Keyphrases
  • brain metastases
  • small cell lung cancer
  • poor prognosis
  • stem cells
  • papillary thyroid
  • single cell
  • long non coding rna