Characterization of the immune microenvironment in brain metastases from different solid tumors.
Jinling JiangLihong WuFei YuanJun JiXiaojing LinWanning YangJunwei WuMin ShiHui YangYanna MaXue SongZhenggang ZhuHenghui ZhangJun ZhangPublished in: Cancer medicine (2020)
This study presents an immune landscape of brain metastases from different cancer types. With high RNA expression levels of PD-1/PD-L1 axis and immune infiltration in brain metastases, it would be worthwhile to explore the efficacy of immune checkpoint blockade for lung cancer patients with intracranial metastases.