Re-identification and Characterization of Multidrug-Resistant Corynebacterium haemomassiliense-Like Organisms from Humans.
Hyeri SeokJi-Young ChoiMichidmaral GanboldJong Hyun ShinJooyun KimWon Suk ChoiDae Won ParkKwan Soo KoPublished in: Current microbiology (2023)
Recently, non-diphtheriae Corynebacterium spp. have been increasingly reported in patients. In addition, several novel species of Corynebacterium isolated from humans. Here, we report two cases of human infections caused by Corynebacterium haemomassiliense-like organisms, which had not been identified at the species level by MALDI-TOF MS analysis. They were revealed to be closely related to C. haemomassiliense, a recently described species by three housekeeping genes (16S rRNA, rpoB, and gyrA) and phenotypic features. Both strains were multidrug-resistant but susceptible to vancomycin, meropenem, and linezolid. Our report suggests that human infections by the recently described Corynebacterium species may not be limited to a specific region, in addition to difficulty of classifying the genus Corynebacterium.
Keyphrases
- multidrug resistant
- gram negative
- endothelial cells
- end stage renal disease
- drug resistant
- acinetobacter baumannii
- induced pluripotent stem cells
- chronic kidney disease
- escherichia coli
- newly diagnosed
- mass spectrometry
- pluripotent stem cells
- genetic diversity
- klebsiella pneumoniae
- prognostic factors
- gene expression
- genome wide
- single cell
- staphylococcus aureus
- patient reported outcomes
- patient reported
- transcription factor
- pseudomonas aeruginosa
- dna methylation
- drug induced
- genome wide identification