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Research Progress on the Mechanism of the Antitumor Effects of Cannabidiol.

Li MaMengke LiuChuntong LiuHuachang ZhangShude YangJing AnGuiwu QuShuling SongQizhi Cao
Published in: Molecules (Basel, Switzerland) (2024)
Cannabidiol (CBD), a non-psychoactive ingredient extracted from the hemp plant, has shown therapeutic effects in a variety of diseases, including anxiety, nervous system disorders, inflammation, and tumors. CBD can exert its antitumor effect by regulating the cell cycle, inducing tumor cell apoptosis and autophagy, and inhibiting tumor cell invasion, migration, and angiogenesis. This article reviews the proposed antitumor mechanisms of CBD, aiming to provide references for the clinical treatment of tumor diseases and the rational use of CBD.
Keyphrases
  • cell cycle
  • cell proliferation
  • oxidative stress
  • signaling pathway
  • cell death
  • endothelial cells
  • systematic review
  • randomized controlled trial
  • endoplasmic reticulum stress
  • depressive symptoms
  • wound healing