Immuno-PET Molecular Imaging of RANKL in Cancer.
Jonatan DewulfChristel VangestelYannick VerhoevenJorrit De WaeleKaren ZwaenepoelPeter A van DamFilipe ElvasTim Van den WyngaertPublished in: Cancers (2021)
[89Zr]Zr-DFO-AMG162 can detect heterogeneous RANKL expression in the TME of human cancer xenografts, supporting further translation of RANKL immuno-PET to evaluate tumor RANKL distribution in patients.
Keyphrases
- pet imaging
- papillary thyroid
- nuclear factor
- bone loss
- end stage renal disease
- squamous cell
- newly diagnosed
- computed tomography
- endothelial cells
- poor prognosis
- chronic kidney disease
- ejection fraction
- pet ct
- peritoneal dialysis
- prognostic factors
- lymph node metastasis
- squamous cell carcinoma
- immune response
- patient reported outcomes
- long non coding rna
- binding protein