Outcomes of COVID-19 and risk factors in patients with cancer.
Manju SengarGirish ChinnaswamyPriya RanganathanApurva AshokShilpushp BhosaleSanjay BiswasPankaj ChaturvediChetan DhamneJigeeshu DivatiaKarishma D'SaHasmukh JainSarbani LaskarNirmalya Roy MoulikNaveen MummudiSindhu NairLingaraj NayakPrakash R NayakShraddha PatkarPreeti PawaskarAnant RamaswamyOmshree ShettyArjun SinghEpari SridharJayashree ThoratRajendra BadweConjeevaram S Prameshnull nullPublished in: Nature cancer (2022)
Patients with cancer are at higher risk for adverse coronavirus disease 2019 (COVID-19) outcomes. Here, we studied 1,253 patients with cancer, who were diagnosed with severe acute respiratory syndrome coronavirus 2 at a tertiary referral cancer center in India. Most patients had mild disease; in our settings, recent cancer therapies did not impact COVID-19 outcomes. Advancing age, smoking history, concurrent comorbidities and palliative intent of treatment were independently associated with severe COVID-19 or death. Thus, our study provides useful insights into cancer management during the COVID-19 pandemic.
Keyphrases
- coronavirus disease
- respiratory syndrome coronavirus
- sars cov
- papillary thyroid
- squamous cell
- risk factors
- end stage renal disease
- chronic kidney disease
- primary care
- lymph node metastasis
- ejection fraction
- radiation therapy
- prognostic factors
- metabolic syndrome
- smoking cessation
- adipose tissue
- young adults
- patient reported
- adverse drug
- advanced cancer