[Prognostic model for assessing the human glioma cell malignancy grade based on MDM2, MELK, SOX2, CDK4, DR5 and OCT4 gene expression].

Ekaterina Evgenyevna Tyagunova S F Drozd O V Kalennik N S Samoylenkova E A Savchenko Gleb V Danilov Galina Valerievna Pavlova

Published in: Zhurnal voprosy neirokhirurgii imeni N. N. Burdenko (2023)

We obtained a prognostic model for assessing the grade III and IV glioma cell malignancy based on expression of marker genes MDM2, MELK, SOX2, CDK4, DR5 and OCT4. Predictive accuracy was 83% (Akaike information criterion -55.125).

Keyphrases

gene expression
single cell
stem cells
cell therapy
transcription factor
cell cycle
endothelial cells
optical coherence tomography
dna methylation
genome wide
healthcare
mesenchymal stem cells
cell proliferation
pluripotent stem cells