Respiratory muscle fatigability in patients with spinal muscular atrophy.

Kim Kant-SmitsErik H J HulzebosLaura E HabetsFay-Lynn AsselmanEsther S VeldhoenRuben P A van EijkJanke F de GrootW Ludo van der PolBart Bartels

Published in: Pediatric pulmonology (2022)

Patients with SMA demonstrate a dose-dependent increase in RMF without severe increase in exercise-induced muscle weakness or perceived fatigue. Inspiratory muscle loading in patients with SMA seems feasible and its potential to stabilize or improve respiratory function in patients with SMA needs to be determined in further research.

Keyphrases

skeletal muscle
depressive symptoms
physical activity
social support
early onset
respiratory tract
sleep quality