Transcriptomic analysis of primate placentas and novel rhesus trophoblast cell lines informs investigations of human placentation.
Jimi L RosenkrantzJessica E GaffneyVictoria H J RobertsLucia CarboneShawn L ChavezPublished in: BMC biology (2021)
Overall, our findings help elucidate the molecular translatability between human and rhesus placenta and reveal notable expression differences in several HPGs and genes implicated in pregnancy complications that should be considered when using the rhesus animal model to study normal and pathological human placentation.