The prognostic significance of KRAS and BRAF mutation status in Korean colorectal cancer patients.

Daeyoun David WonJae Im LeeIn Kyu LeeSeong-Taek OhEun Sun JungSung Hak Lee

Published in: BMC cancer (2017)

BRAF mutation, rather than KRAS, was a significant prognostic factor in Korean CRC patients at both early and advanced stages. The subgroup analysis for MSI did not show significant differences in clinical outcome. BRAF should be included in future larger prospective biomarker studies on CRC.

Keyphrases

prognostic factors
wild type
end stage renal disease
metastatic colorectal cancer
newly diagnosed
ejection fraction
chronic kidney disease
randomized controlled trial
current status
patient reported
open label