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Photocatalyst-free visible-light-induced highly selective acylation of purine nucleosides at the C6 position.

Luohao LiHuiqin ZhengFeixiang GuoZehui FangQianqian SunJing LiQinghe GaoTao ZhangLizhen Fang
Published in: Chemical communications (Cambridge, England) (2023)
A protocol for visible-light-induced C-H acylation selectively at the C6 position of purine nucleosides with aldehydes under photocatalyst-free conditions was established herein. This protocol allows the green, mild, and efficient functionalization of various purine nucleosides with a broad range of alkyl and aryl aldehydes.
Keyphrases
  • visible light
  • randomized controlled trial
  • highly efficient