There is a high prevalence of hypovitaminosis D in patients with back pain regardless of whether or not they require surgical intervention. Furthermore, the risk of hypovitaminosis D is not limited to individuals with traditional clinical risk factors. Vitamin D plays an essential role in bone formation, maintenance, and remodeling, as well as muscle function. Published data indicate that hypovitaminosis D could adversely affect bone formation and muscle function in multiple ways. The literature contains numerous reports of myopathy and/or musculoskeletal pain associated with hypovitaminosis D. In terms of spinal fusion outcomes, a patient may have a significant decrease in pain and the presence of de novo bone on an X-ray, yet their functional ability may remain severely limited. Hypovitaminosis D may be a contributing factor to the persistent postoperative pain experienced by these patients. Indeed, hypovitaminosis D is not asymptomatic, and symptoms can manifest themselves independent of the musculoskeletal pathological changes associated with conditions like osteomalacia. It appears that vitamin D status is routinely overlooked, and there is a need to raise awareness about its importance among all healthcare practitioners who treat spine patients.
Keyphrases
- end stage renal disease
- healthcare
- risk factors
- ejection fraction
- postoperative pain
- chronic kidney disease
- chronic pain
- newly diagnosed
- systematic review
- skeletal muscle
- prognostic factors
- randomized controlled trial
- primary care
- peritoneal dialysis
- emergency department
- type diabetes
- magnetic resonance
- spinal cord
- depressive symptoms
- computed tomography
- machine learning
- social media
- physical activity
- insulin resistance
- postmenopausal women
- electronic health record
- health information
- glycemic control
- bone loss