Tranexamic acid versus oxytocin for primary postpartum Haemorrhage in the out-of-hospital setting: A systematic review with implications for rural practice.
Megan De SilvaGabrielle MizziEmily PottsJayden WebbElizabeth ThyerNavindhra NaidooPublished in: The Australian journal of rural health (2024)
There is no difference in blood loss, neonatal or maternal mortality or morbidity, or need for further interventions, when using oxytocin or TXA compared to no intervention, or compared to standard care, for PPH. Further studies are needed on the efficacy of these drugs, and alternate or co-drug therapies, for PPH in the out-of-hospital environment and rural clinical practice.
Keyphrases
- healthcare
- clinical practice
- south africa
- adverse drug
- randomized controlled trial
- quality improvement
- palliative care
- acute care
- primary care
- physical activity
- cardiovascular events
- risk factors
- drug induced
- emergency department
- cardiovascular disease
- type diabetes
- pain management
- body mass index
- chronic pain
- affordable care act