Organoid Cultures as Preclinical Models of Non-Small Cell Lung Cancer.

Ruoshi ShiNikolina RadulovichChristine NgGeoffrey LiuHirotsugu NotsudaMichael CabaneroSebastiao N Martins-FilhoVibha RaghavanQuan LiArvind Singh MerJoshua C RosenMing LiYu-Hui WangLaura TamblynNhu-An PhamBenjamin Haibe-KainsNadeem MoghalMing-Sound Tsao

Published in: Clinical cancer research : an official journal of the American Association for Cancer Research (2019)

Our panel of NSCLC organoids closely recapitulates the genomics and biology of patient tumors, and is a potential platform for drug testing and biomarker validation.

Keyphrases

small cell lung cancer
case report
single cell
high throughput
advanced non small cell lung cancer
cell therapy
stem cells
risk assessment
mesenchymal stem cells
bone marrow
climate change
tyrosine kinase