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Organoid Cultures as Preclinical Models of Non-Small Cell Lung Cancer.

Ruoshi ShiNikolina RadulovichChristine NgGeoffrey LiuHirotsugu NotsudaMichael CabaneroSebastiao N Martins-FilhoVibha RaghavanQuan LiArvind Singh MerJoshua C RosenMing LiYu-Hui WangLaura TamblynNhu-An PhamBenjamin Haibe-KainsNadeem MoghalMing Sound Tsao
Published in: Clinical cancer research : an official journal of the American Association for Cancer Research (2019)
Our panel of NSCLC organoids closely recapitulates the genomics and biology of patient tumors, and is a potential platform for drug testing and biomarker validation.
Keyphrases
  • small cell lung cancer
  • case report
  • single cell
  • high throughput
  • advanced non small cell lung cancer
  • cell therapy
  • stem cells
  • risk assessment
  • mesenchymal stem cells
  • bone marrow
  • climate change
  • tyrosine kinase