LRP5 gene polymorphisms and radiographic joint damage in rheumatoid arthritis patients.
Miguel BernardesC DurãesA OliveiraM J MartinsR LucasL CostaJ G PereiraI RamosJ C MachadoF Simões-VenturaPublished in: Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA (2018)
Significant associations between LRP5 SNPs (p.A1330V, p.N740N, and p.V667M) and the severity of radiographic damage reinforce the evidence of bone destruction heritability in RA.