LRP5 gene polymorphisms and radiographic joint damage in rheumatoid arthritis patients.

Miguel BernardesC DurãesA OliveiraM J MartinsR LucasL CostaJ G PereiraI RamosJ C MachadoF Simões-Ventura

Published in: Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA (2018)

Significant associations between LRP5 SNPs (p.A1330V, p.N740N, and p.V667M) and the severity of radiographic damage reinforce the evidence of bone destruction heritability in RA.

Keyphrases

rheumatoid arthritis patients
disease activity
rheumatoid arthritis
oxidative stress
systemic lupus erythematosus
ankylosing spondylitis
bone mineral density
genome wide
low density lipoprotein
gene expression
soft tissue
dna methylation
interstitial lung disease