Vitamin D3 attenuates oxidative stress and regulates glucose level and leukocyte count in a semi-chronic streptozotocin-induced diabetes model.

Maja Mitrašinović-Brulić Amela Dervišević Asija Zaciragic Muhamed Fočak Amina Valjevac Almira Hadžović-Džuvo Damir Suljevic

Published in: Journal of diabetes and metabolic disorders (2021)

Vit-D3 treatment has important therapeutic effects; among many others it can attenuate oxidative stress and ameliorate the hyperglycemic state in the STZ-induced rat diabetic model, which is promising for further clinical trials.

Keyphrases

diabetic rats
oxidative stress
clinical trial
type diabetes
ischemia reperfusion injury
dna damage
induced apoptosis
high glucose
cardiovascular disease
peripheral blood
randomized controlled trial
adipose tissue
high fat diet
insulin resistance
blood pressure
glycemic control
double blind