Transient elastography and controlled attenuation parameter to evaluate hepatic steatosis and liver stiffness in postpartum patients.
Farrah Naz HussainEmma RosenbluthKristina Martimucci FeldmanTirtza Spiegel StraussEmily SchneiderEmily Schmidt-BeauchatClara Rodriguez-RivasLois BrustmanTatyana KushnerPublished in: The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians (2023)
Patients with preeclampsia, type 2 diabetes, and elevated ALT were more likely to have elevated postpartum liver stiffness. Pregravid BMI ≥25 and ≥30 were associated with increased liver steatosis, although did not impact liver stiffness. GDM was not associated with increased liver stiffness or steatosis. Consideration should be made for screening pregnant patients with preeclampsia, type 2 DM and overweight or obese BMI for liver disease in the postpartum period with potential for lifestyle intervention.
Keyphrases
- type diabetes
- insulin resistance
- weight loss
- end stage renal disease
- metabolic syndrome
- body mass index
- randomized controlled trial
- early onset
- physical activity
- weight gain
- high fat diet
- adipose tissue
- chronic kidney disease
- pregnant women
- newly diagnosed
- skeletal muscle
- prognostic factors
- risk assessment
- patient reported outcomes
- high fat diet induced
- patient reported
- climate change
- pregnancy outcomes