Intergenerational transmission of stress: Multi-domain stressors from maternal childhood and pregnancy predict children's mental health in a racially and socioeconomically diverse, multi-site cohort.
Nicole R BushAmanda Noroña-ZhouMichael CocciaKristen L RuddShaikh I AhmadChristine T LoftusShanna H SwanRuby H N NguyenEmily S BarrettFrances A TylavskyW Alex MasonCatherine J KarrSheela SathyanarayanaKaja Z LeWinnPublished in: Social psychiatry and psychiatric epidemiology (2023)
Findings confirm that maternal exposure to CTE and PSLE are independently associated with child mental health, and history of CTE exacerbates the risk associated with PSLE, highlighting intergenerational risk pathways for early psychopathology. Given the prevalence of these exposures, prevention and intervention programs that reduce childhood trauma and stress during pregnancy will likely positively impact women's and their children's health.
Keyphrases
- mental health
- pregnancy outcomes
- young adults
- public health
- mental illness
- birth weight
- randomized controlled trial
- healthcare
- risk factors
- pregnant women
- childhood cancer
- polycystic ovary syndrome
- type diabetes
- air pollution
- adipose tissue
- climate change
- physical activity
- body mass index
- risk assessment
- heat stress
- human health
- health promotion
- anorexia nervosa