Comparison of the effects of dexmedetomidine and nitroglycerin on cerebral oxygen saturation using near-infrared spectroscopy in patients undergoing controlled hypotensive anaesthesia: A randomised controlled non-inferiority trial.

J Koteswara Rao Swati Chhabra Sadik Mohammed Pradeep K Bhatia Shilpa Goyal Rakesh Kumar

Published in: Indian journal of anaesthesia (2024)

Dexmedetomidine is non-inferior to nitroglycerin in terms of the occurrence of cerebral desaturation events when used for controlled hypotensive anaesthesia in head and neck surgeries.

Keyphrases

patients undergoing
subarachnoid hemorrhage
study protocol
cardiac surgery
risk assessment
clinical trial
cerebral ischemia
randomized controlled trial
brain injury
phase ii
acute kidney injury
cerebral blood flow
open label
double blind