Two-year real-life efficacy, tolerability and safety of dimethyl fumarate in an Italian multicentre study.

Giulia MallucciP AnnovazziS MianteV Torri-ClericiM MattaS La GioiaR CavarrettaV ManteroG CostantiniV D'AmbrosioM ZaffaroniA GhezziP PeriniS RossiA BertolottoM R RottoliM RovarisR BalgeraP CavallaC MontomoliR Bergamaschi

Published in: Journal of neurology (2018)

Our post-market study corroborated that DMF is a safe and effective drug. Additionally, the study suggested that naïve patients strongly benefit from DMF and that DMF improved ARR also in patients who were horizontally switched from injectable therapies due to tolerability and efficacy issues.

Keyphrases

end stage renal disease
chronic kidney disease
newly diagnosed
open label
ejection fraction
prognostic factors
emergency department
peritoneal dialysis
randomized controlled trial
health insurance
patient reported outcomes
drug induced
double blind
adverse drug
patient reported