Impact of HIV and peripartum period on Mycobacterium tuberculosis infection detection.
Jaclyn N EscuderoJerphason MechaBarbra A RichardsonElizabeth Maleche-ObimboDaniel MatemoJohn KinuthiaGrace C John-StewartSylvia M LaCoursePublished in: The Journal of infectious diseases (2023)
QFT-Plus had higher TBI diagnostic yield than TST in peripartum women with/without HIV. Peripartum QFT-Plus + prevalence was stable and less influenced by HIV than TST. Mtb-specific IFN-γ responses were dynamic and lower among WHIV. TBI test conversion incidence was high between pregnancy and early postpartum, potentially due to postpartum immune recovery.
Keyphrases
- antiretroviral therapy
- mycobacterium tuberculosis
- hiv positive
- hiv infected
- hiv testing
- human immunodeficiency virus
- hepatitis c virus
- hiv aids
- traumatic brain injury
- men who have sex with men
- risk factors
- pulmonary tuberculosis
- immune response
- south africa
- severe traumatic brain injury
- mild traumatic brain injury
- real time pcr
- quantum dots