A Prospective European Trial Comparing Laparotomy, Laparoscopy, Robotic-Assisted, and Transanal Total Mesorectal Excision Procedures in High-Risk Patients with Rectal Cancer: The RESET Trial.

Philippe RouanetMario GuerrieriPablo LemercierEmre BalikEddy CotteAntonino SpinelliMarcos Gómez-RuizAlbert WolthuisEmilio BertaniAnne Duboisnull null

Published in: Annals of surgery (2024)

The RESET trial yielded high-quality results despite focusing on HRPs. Minimally invasive procedures showed similar sphincter-sparing procedure outcomes, but LTME included patients with more favorable tumors. Oncologic and functional outcomes will be evaluated at 2 years (ClinicalTrials.gov, ID: NCT03574493).

Keyphrases

rectal cancer
minimally invasive
robot assisted
locally advanced
phase iii
study protocol
phase ii
clinical trial
randomized controlled trial
open label
adipose tissue
type diabetes
radiation therapy
insulin resistance
urinary incontinence
double blind
placebo controlled