Definite and indeterminate nonalcoholic steatohepatitis share similar clinical features and prognosis: A longitudinal study of 1893 biopsy-proven nonalcoholic fatty liver disease subjects.
Javier AmpueroRocío AllerRocío Gallego-DuránJavier CrespoJavier AbadÁgueda González-RodríguezJudith Gómez-CamareroJoan CaballeríaOreste Lo IaconoLuis IbañezJavier García-SamaniegoRosa Martín-MateosRubén FrancésConrado Fernández-RodríguezMoisés DiagoGerman SorianoRaúl Jesús AndradeRaquel LatorreFrancisco JorqueraRosa M MorillasDesam EscuderoPamela EstévezManuel Hernández-GuerraSalvador AugustínMaría Jesús Pareja-MegiaJesus Maria BanalesPatricia AspichuetaSalvador BenllochJosé Miguel RosalesJavier SalmerónJuan TurnesManuel Romero-Gómeznull nullPublished in: Liver international : official journal of the International Association for the Study of the Liver (2021)
The prevalence of steatohepatitis decreased in advanced liver disease. However, most of these patients showed some inflammatory activity histologically and had metabolic disturbances. These findings should be considered in clinical trials whose main aim is to prevent cirrhosis progression and complications, liver transplant and death.