Renal AAV2-Mediated Overexpression of Long Non-Coding RNA H19 Attenuates Ischemic Acute Kidney Injury Through Sponging of microRNA-30a-5p.

George HaddadMalte KöllingUrs A WegmannAngela DettlingHarald SeegerRoland SchmittInga Soerensen-ZenderHermann HallerAndreas D KistlerAnne DueckStefan EngelhardtThomas Thum Thomas F Mueller Rudolf P Wüthrich Johan M Lorenzen

Published in: Journal of the American Society of Nephrology : JASN (2021)

H19 overexpression confers protection against renal injury by stimulating proangiogenic signaling. H19 overexpression may be a promising future therapeutic option in the treatment of patients with ischemic AKI.

Keyphrases

long non coding rna
acute kidney injury
cell proliferation
poor prognosis
transcription factor
cardiac surgery
cerebral ischemia
current status
subarachnoid hemorrhage
brain injury
blood brain barrier