The association between Matrix Metallo-proteinases-9 (MMP-9) gene family polymorphisms and risk of Coronary Artery Disease (CAD): a systematic review and meta-analysis.
Reza Hassanzadeh-MakouiBahman RaziSaeed AslaniDanyal ImaniSeyedeh Samaneh TabaeePublished in: BMC cardiovascular disorders (2020)
Our meta-analysis revealed that MMP-9 (C1562T) SNP conferred a susceptibility risk for CAD in the overall analysis and Asian population. The overall analysis and subgroup analysis of the other three SNPs reject the association between MMP-9 polymorphisms and the risk of CAD. Although the results should interpret with caution because of small sample size of included studies in these three SNPs.
Keyphrases
- coronary artery disease
- systematic review
- genome wide
- percutaneous coronary intervention
- cardiovascular events
- cell migration
- coronary artery bypass grafting
- type diabetes
- clinical trial
- case control
- randomized controlled trial
- single cell
- gene expression
- meta analyses
- multidrug resistant
- study protocol
- high density