The Multiple Effects of Vitamin D against Chronic Diseases: From Reduction of Lipid Peroxidation to Updated Evidence from Clinical Studies.
Massimiliano BerrettaVincenzo QuagliarielloAlessia BignucoloSergio FacchiniNicola MaureaRaffaele Di FranciaFrancesco FioricaSaman SharifiSilvia BressanSara N RichterValentina CamozziLuca RinaldiCarla ScaroniMonica MontopoliPublished in: Antioxidants (Basel, Switzerland) (2022)
Vitamin D significantly reduces the pro-oxidant systemic and tissue biomarkers involved in the development, progression, and recurrence of chronic cardiometabolic disease and cancer. The overall picture of this review provides the basis for new randomized controlled trials of oral vitamin D supplementation in patients with cancer and infectious, neurodegenerative, and cardiovascular diseases aimed at reducing risk factors for disease recurrence and improving quality of life.