Novel perspectives of testosterone therapy in men with functional hypogonadism: traversing the gaps of knowledge.
Kristina Groti AntoničMichael ZitzmannPublished in: The aging male : the official journal of the International Society for the Study of the Aging Male (2023)
This focused review article aims to present a comprehensive update on the latest data concerning the innovative aspects of testosterone therapy in males with functional hypogonadism, particularly in the context of type 2 diabetes and/or obesity. Additionally, it will delve into the cardiovascular safety of such interventions within this high-risk demographic, with a special emphasis on insights gleaned from the TRAVERSE trial.
Keyphrases
- replacement therapy
- smoking cessation
- healthcare
- metabolic syndrome
- insulin resistance
- clinical trial
- physical activity
- weight loss
- electronic health record
- randomized controlled trial
- body mass index
- adipose tissue
- big data
- mesenchymal stem cells
- high fat diet induced
- skeletal muscle
- phase ii
- cell therapy
- open label
- artificial intelligence