Discrimination of FCGR2B polymorphism without coamplification of FCGR2A and FCGR2C genes.

F BonattiA AdorniA PercesepeDavide Martorana

Published in: International journal of immunogenetics (2017)

The FCGR locus is characterized by high polymorphism and sequence homology. In particular, the Ile232Thr polymorphism in the FCGR2B gene results in inaccurate genotyping in most published papers. The purpose of the study was to develop an accurate genotyping assay able to discriminate this polymorphism.

Keyphrases

genome wide
high throughput
high resolution
genome wide identification
randomized controlled trial
systematic review
gene expression
amino acid