Proteomic profiling of longitudinal changes in kidney function among middle-aged and older men and women: the KORA S4/F4/FF4 study.

Jie-Sheng LinJana NanoAgnese PetreraStefanie M HauckTanja ZellerWolfgang KoenigChristian L MüllerAnnette PetersBarbara Thorand

Published in: BMC medicine (2023)

We reported 21 proteins associated with kidney function decline and incident CKD and provided preliminary evidence suggesting a potential causal association between TNFRSF11A and kidney function decline. Further Mendelian randomization studies are needed to establish a conclusive causal association.

Keyphrases

cardiovascular disease
chronic kidney disease
cross sectional
middle aged
human health
climate change
case control