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CFTR reduces the proliferation of lung adenocarcinoma and is a strong predictor of survival in both smokers and non-smokers.

Qingyang XiaoStefania KoutsilieriDespoina-Christina SismanoglouVolker Martin Lauschke
Published in: Journal of cancer research and clinical oncology (2022)
These results suggest that CFTR acts as a pharmacologically activatable tumor suppressor and constitutes a promising target for adjuvant therapy in lung adenocarcinoma.
Keyphrases
  • cystic fibrosis
  • smoking cessation
  • signaling pathway
  • free survival