Volker Martin Lauschke (Volker Lauschke, Volker M Lauschke, Volker M Lauschke)

ResearcherID Loop profile Scopus Author ID ORCID

Publication Activity (10 Years)

Years Active: 2016-2024
Publications (10 Years): 111

Top Venues

Clinical pharmacology and therapeutics

The pharmacogenomics journal

Nature metabolism

Drug metabolism and disposition: the biological fate of chemicals

Karolinska Institutet

FernUniversität in Hagen (BSC)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Karolinska Institutet Jan 01 2017

Sweden

Assistant Professor :: Physiology and Pharmacology

Karolinska Institutet - Dec 31 2016

Sweden

Postdoctoral researcher :: Physiology and Pharmacology

EMBL

Germany

Postdoctoral researcher :: Developmental biology

Education History

FernUniversität in Hagen

Germany

BSC

EMBL

Germany

PHD :: Developmental Biology

Publications

Chen Xing, Aurino Kemas, Evgeniya Mickols, Kathrin Klein, Per Artursson, Volker Martin Lauschke
The choice of ultra-low attachment plates impacts primary human and primary canine hepatocyte spheroid formation, phenotypes, and function. Biotechnology journal 19 (2) (2024)
Yitian Zhou, Sebastian Pirmann, Volker Martin Lauschke
APF2: an improved ensemble method for pharmacogenomic variant effect prediction. The pharmacogenomics journal 24 (3) (2024)
Mahamadou D Camara, Yitian Zhou, Antoine Dara, Mamadou M Tékété, Taís Nóbrega de Sousa, Sékou Sissoko, Laurent Dembele, Nouhoun Ouologuem, Amadou Hamidou Togo, Mohamed L Alhousseini, Bakary Fofana, Issaka Sagara, Abdoulaye A Djimde, Pedro J Gil, Volker Martin Lauschke
Population-specific variations in KCNH2 predispose patients to delayed ventricular repolarization upon dihydroartemisinin-piperaquine therapy. Antimicrobial agents and chemotherapy 68 (5) (2024)
Min Yu, Weiming Li, Yunru Yu, Yu Zhao, Lizhi Xiao, Volker Martin Lauschke, Yiyu Cheng, Xingcai Zhang, Yi Wang
Deep learning large-scale drug discovery and repurposing. Nature computational science 4 (8) (2024)
Mahamadou D Camara, Yitian Zhou, Antoine Dara, Mamadou M Tékété, Taís Nóbrega de Sousa, Sékou Sissoko, Laurent Dembele, Nouhoun Ouologuem, Amadou Hamidou Togo, Mohamed L Alhousseini, Bakary Fofana, Issaka Sagara, Abdoulaye A Djimde, Pedro J Gil, Volker Martin Lauschke
Population-specific variations in KCNH2 predispose patients to delayed ventricular repolarization upon dihydroartemisinin-piperaquine therapy. Antimicrobial agents and chemotherapy 68 (5) (2024)
Mahamadou D Camara, Yitian Zhou, Antoine Dara, Mamadou M Tékété, Taís Nóbrega de Sousa, Sékou Sissoko, Laurent Dembele, Nouhoun Ouologuem, Amadou Hamidou Togo, Mohamed L Alhousseini, Bakary Fofana, Issaka Sagara, Abdoulaye A Djimde, Pedro J Gil, Volker Martin Lauschke
Population-specific variations in KCNH2 predispose patients to delayed ventricular repolarization upon dihydroartemisinin-piperaquine therapy. Antimicrobial agents and chemotherapy 68 (5) (2024)
Nayere Taebnia, Volker Martin Lauschke
Hepatic Inhibition of ANGPTL3 Mimics the Molecular Hallmarks of Hypothyroidism. Arteriosclerosis, thrombosis, and vascular biology 44 (5) (2024)
Magnus Ingelman-Sundberg, Volker Martin Lauschke
Individualized Pharmacotherapy Utilizing Genetic Biomarkers and Novel In Vitro Systems As Predictive Tools for Optimal Drug Development and Treatment. Drug metabolism and disposition: the biological fate of chemicals 52 (6) (2024)
Mahamadou D Camara, Yitian Zhou, Antoine Dara, Mamadou M Tékété, Taís Nóbrega de Sousa, Sékou Sissoko, Laurent Dembele, Nouhoun Ouologuem, Amadou Hamidou Togo, Mohamed L Alhousseini, Bakary Fofana, Issaka Sagara, Abdoulaye A Djimde, Pedro J Gil, Volker Martin Lauschke
Population-specific variations in KCNH2 predispose patients to delayed ventricular repolarization upon dihydroartemisinin-piperaquine therapy. Antimicrobial agents and chemotherapy 68 (5) (2024)
Vanessa M Monteil, Shane C Wright, Matheus Dyczynski, Max J Kellner, Sofia K Appelberg, Sebastian Wolfgang Platzer, Ahmed Ibrahim, Hyesoo Kwon, Ioannis Pittarokoilis, Mattia Mirandola, Georg Michlits, Stéphanie Devignot, Elizabeth G Elder, Samir Abdurahman, Sándor Bereczky, Binnur Bagci, Sonia Youhanna, Teodor Aastrup, Volker Martin Lauschke, Cristiano Salata, Nazif Elaldi, Friedemann Weber, Nuria Montserrat, David W Hawman, Heinrich Feldmann, Moritz Horn, Josef M Penninger, Ali Mirazimi
Crimean-Congo haemorrhagic fever virus uses LDLR to bind and enter host cells. Nature microbiology 9 (6) (2024)
Min Yu, Weiming Li, Yunru Yu, Yu Zhao, Lizhi Xiao, Volker Martin Lauschke, Yiyu Cheng, Xingcai Zhang, Yi Wang
Deep learning large-scale drug discovery and repurposing. Nature computational science 4 (8) (2024)
Lin Guo, JiaTing Ma, MingXuan Xiao, JiaYi Liu, ZhiYu Hu, Shuang Xia, Ning Li, Yan Yang, Hui Gong, Yang Xi, Rao Fu, Pei Jiang, ChunGuang Xia, Volker Martin Lauschke, Miao Yan
The involvement of the Stat1/Nrf2 pathway in exacerbating Crizotinib-induced liver injury: implications for ferroptosis. Cell death & disease 15 (8) (2024)
Christian Sommerauer, Carlos J Gallardo-Dodd, Christina Savva, Linnea Hases, Madeleine Birgersson, Rajitha Indukuri, Joanne X Shen, Pablo Carravilla, Keyi Geng, Jonas Nørskov Søndergaard, Clàudia Ferrer-Aumatell, Grégoire Mercier, Erdinc Sezgin, Marion Korach-André, Carl Petersson, Hannes Hagström, Volker Martin Lauschke, Amena Archer, Cecilia Williams, Claudia Kutter
Estrogen receptor activation remodels TEAD1 gene expression to alleviate hepatic steatosis. Molecular systems biology (2024)
Shane C Wright, Charlotte Avet, Supriya A Gaitonde, Itziar Muneta-Arrate, Christian Le Gouill, Mireille Hogue, Billy Breton, Stefania Koutsilieri, Rebeca Diez Alarcia, Madeleine Héroux, Volker Martin Lauschke, Michel Bouvier
Conformation- and activation-based BRET sensors differentially report on GPCR-G protein coupling. Science signaling 17 (841) (2024)
Magnus Ingelman-Sundberg, Volker Martin Lauschke
Individualized pharmacotherapy utilizing genetic biomarkers and novel in vitro systems as predictive tools for optimal drug development and treatment . Drug metabolism and disposition: the biological fate of chemicals (2024)
Vanessa M Monteil, Shane C Wright, Matheus Dyczynski, Max J Kellner, Sofia K Appelberg, Sebastian Wolfgang Platzer, Ahmed Ibrahim, Hyesoo Kwon, Ioannis Pittarokoilis, Mattia Mirandola, Georg Michlits, Stéphanie Devignot, Elizabeth G Elder, Samir Abdurahman, Sándor Bereczky, Binnur Bagci, Sonia Youhanna, Teodor Aastrup, Volker Martin Lauschke, Cristiano Salata, Nazif Elaldi, Friedemann Weber, Nuria Montserrat, David W Hawman, Heinrich Feldmann, Moritz Horn, Josef M Penninger, Ali Mirazimi
Crimean-Congo haemorrhagic fever virus uses LDLR to bind and enter host cells. Nature microbiology (2024)
Yitian Zhou, Volker Martin Lauschke
Next-generation sequencing in pharmacogenomics - fit for clinical decision support? Expert review of clinical pharmacology 17 (3) (2024)
Francesca Lazzeri-Barcelo, Nuria Oliva-Vilarnau, Marion Baniol, Barbara Leibiger, Olaf Bergmann, Volker Martin Lauschke, Ingo B Leibiger, Noah Moruzzi, Per-Olof Berggren
Intraocular liver spheroids for non-invasive high-resolution in vivo monitoring of liver cell function. Nature communications 15 (1) (2024)
Hüsün S Kizilkaya, Kimmie V Sørensen, Jakob Sture Madsen, Peter Lindquist, Jonathan D Douros, Jette Bork-Jensen, Alessandro Berghella, Peter A Gerlach, Laerke Smidt Gasbjerg, Jacek Mokrosinski, Stephanie A Mowery, Patrick J Knerr, Brian Finan, Jonathan E Campbell, David A D'Alessio, Diego Perez-Tilve, Felix Faas, Signe Mathiasen, Jørgen Rungby, Henrik Toft Sorensen, Allan Vaag, Jens Steen Nielsen, Jens-Christian Holm, Jeannet Lauenborg, Nis Peter Damm, Oluf Pedersen, Allan Linneberg, Bolette Hartmann, Jens Juul Holst, Torben Hansen, Shane C Wright, Volker Martin Lauschke, Niels Grarup, Alexander Sebastian Hauser, Mette Marie Rosenkilde
Characterization of genetic variants of GIPR reveals a contribution of β-arrestin to metabolic phenotypes. Nature metabolism 6 (7) (2024)
Yitian Zhou, Sebastian Pirmann, Volker Martin Lauschke
APF2: an improved ensemble method for pharmacogenomic variant effect prediction. The pharmacogenomics journal 24 (3) (2024)
Min Yu, Weiming Li, Yunru Yu, Yu Zhao, Lizhi Xiao, Volker Martin Lauschke, Yiyu Cheng, Xingcai Zhang, Yi Wang
Deep learning large-scale drug discovery and repurposing. Nature computational science (2024)
Christian Sommerauer, Carlos J Gallardo-Dodd, Christina Savva, Linnea Hases, Madeleine Birgersson, Rajitha Indukuri, Joanne X Shen, Pablo Carravilla, Keyi Geng, Jonas Nørskov Søndergaard, Clàudia Ferrer-Aumatell, Grégoire Mercier, Erdinc Sezgin, Marion Korach-André, Carl Petersson, Hannes Hagström, Volker Martin Lauschke, Amena Archer, Cecilia Williams, Claudia Kutter
Estrogen receptor activation remodels TEAD1 gene expression to alleviate hepatic steatosis. Molecular systems biology 20 (4) (2024)
Lin Guo, JiaTing Ma, MingXuan Xiao, JiaYi Liu, ZhiYu Hu, Shuang Xia, Ning Li, Yan Yang, Hui Gong, Yang Xi, Rao Fu, Pei Jiang, ChunGuang Xia, Volker Martin Lauschke, Miao Yan
The involvement of the Stat1/Nrf2 pathway in exacerbating Crizotinib-induced liver injury: implications for ferroptosis. Cell death & disease 15 (8) (2024)
Francesca Lazzeri-Barcelo, Nuria Oliva-Vilarnau, Marion Baniol, Barbara Leibiger, Olaf Bergmann, Volker Martin Lauschke, Ingo B Leibiger, Noah Moruzzi, Per-Olof Berggren
Intraocular liver spheroids for non-invasive high-resolution in vivo monitoring of liver cell function. Nature communications 15 (1) (2024)
Vanessa M Monteil, Shane C Wright, Matheus Dyczynski, Max J Kellner, Sofia K Appelberg, Sebastian Wolfgang Platzer, Ahmed Ibrahim, Hyesoo Kwon, Ioannis Pittarokoilis, Mattia Mirandola, Georg Michlits, Stéphanie Devignot, Elizabeth G Elder, Samir Abdurahman, Sándor Bereczky, Binnur Bagci, Sonia Youhanna, Teodor Aastrup, Volker Martin Lauschke, Cristiano Salata, Nazif Elaldi, Friedemann Weber, Nuria Montserrat, David W Hawman, Heinrich Feldmann, Moritz Horn, Josef M Penninger, Ali Mirazimi
Crimean-Congo haemorrhagic fever virus uses LDLR to bind and enter host cells. Nature microbiology 9 (6) (2024)
Nayere Taebnia, Volker Martin Lauschke
Hepatic Inhibition of ANGPTL3 Mimics the Molecular Hallmarks of Hypothyroidism. Arteriosclerosis, thrombosis, and vascular biology (2024)
Shane C Wright, Charlotte Avet, Supriya A Gaitonde, Itziar Muneta-Arrate, Christian Le Gouill, Mireille Hogue, Billy Breton, Stefania Koutsilieri, Rebeca Diez Alarcia, Madeleine Héroux, Volker Martin Lauschke, Michel Bouvier
Conformation- and activation-based BRET sensors differentially report on GPCR-G protein coupling. Science signaling 17 (841) (2024)
Hüsün S Kizilkaya, Kimmie V Sørensen, Jakob Sture Madsen, Peter Lindquist, Jonathan D Douros, Jette Bork-Jensen, Alessandro Berghella, Peter A Gerlach, Laerke Smidt Gasbjerg, Jacek Mokrosinski, Stephanie A Mowery, Patrick J Knerr, Brian Finan, Jonathan E Campbell, David A D'Alessio, Diego Perez-Tilve, Felix Faas, Signe Mathiasen, Jørgen Rungby, Henrik Toft Sorensen, Allan Vaag, Jens Steen Nielsen, Jens-Christian Holm, Jeannet Lauenborg, Nis Peter Damm, Oluf Pedersen, Allan Linneberg, Bolette Hartmann, Jens Juul Holst, Torben Hansen, Shane C Wright, Volker Martin Lauschke, Niels Grarup, Alexander Sebastian Hauser, Mette Marie Rosenkilde
Characterization of genetic variants of GIPR reveals a contribution of β-arrestin to metabolic phenotypes. Nature metabolism (2024)
Vanessa M Monteil, Shane C Wright, Matheus Dyczynski, Max J Kellner, Sofia K Appelberg, Sebastian Wolfgang Platzer, Ahmed Ibrahim, Hyesoo Kwon, Ioannis Pittarokoilis, Mattia Mirandola, Georg Michlits, Stéphanie Devignot, Elizabeth G Elder, Samir Abdurahman, Sándor Bereczky, Binnur Bagci, Sonia Youhanna, Teodor Aastrup, Volker Martin Lauschke, Cristiano Salata, Nazif Elaldi, Friedemann Weber, Nuria Montserrat, David W Hawman, Heinrich Feldmann, Moritz Horn, Josef M Penninger, Ali Mirazimi
Crimean-Congo haemorrhagic fever virus uses LDLR to bind and enter host cells. Nature microbiology 9 (6) (2024)
Magnus Ingelman-Sundberg, Volker Martin Lauschke
Individualized Pharmacotherapy Utilizing Genetic Biomarkers and Novel In Vitro Systems As Predictive Tools for Optimal Drug Development and Treatment. Drug metabolism and disposition: the biological fate of chemicals 52 (6) (2024)
Lena C Preiss, Katrin Georgi, Volker Martin Lauschke, Carl Petersson
Comparison of Human Long-Term Liver Models for Clearance Prediction of Slowly Metabolized Compounds . Drug metabolism and disposition: the biological fate of chemicals (2024)
Lin Guo, JiaTing Ma, MingXuan Xiao, JiaYi Liu, ZhiYu Hu, Shuang Xia, Ning Li, Yan Yang, Hui Gong, Yang Xi, Rao Fu, Pei Jiang, ChunGuang Xia, Volker Martin Lauschke, Miao Yan
The involvement of the Stat1/Nrf2 pathway in exacerbating Crizotinib-induced liver injury: implications for ferroptosis. Cell death & disease 15 (8) (2024)
Yitian Zhou, Sebastian Pirmann, Volker Martin Lauschke
APF2: an improved ensemble method for pharmacogenomic variant effect prediction. The pharmacogenomics journal 24 (3) (2024)
Yitian Zhou, Sebastian Pirmann, Volker Martin Lauschke
APF2: an improved ensemble method for pharmacogenomic variant effect prediction. The pharmacogenomics journal 24 (3) (2024)
Yitian Zhou, Sebastian Pirmann, Volker Martin Lauschke
APF2: an improved ensemble method for pharmacogenomic variant effect prediction. The pharmacogenomics journal 24 (3) (2024)
Yitian Zhou, Volker Martin Lauschke
Next-generation sequencing in pharmacogenomics - fit for clinical decision support? Expert review of clinical pharmacology (2024)
Lena C Preiss, Katrin Georgi, Volker Martin Lauschke, Carl Petersson
Comparison of Human Long-Term Liver Models for Clearance Prediction of Slowly Metabolized Compounds. Drug metabolism and disposition: the biological fate of chemicals 52 (6) (2024)
Hüsün S Kizilkaya, Kimmie V Sørensen, Jakob Sture Madsen, Peter Lindquist, Jonathan D Douros, Jette Bork-Jensen, Alessandro Berghella, Peter A Gerlach, Laerke Smidt Gasbjerg, Jacek Mokrosinski, Stephanie A Mowery, Patrick J Knerr, Brian Finan, Jonathan E Campbell, David A D'Alessio, Diego Perez-Tilve, Felix Faas, Signe Mathiasen, Jørgen Rungby, Henrik Toft Sorensen, Allan Vaag, Jens Steen Nielsen, Jens-Christian Holm, Jeannet Lauenborg, Nis Peter Damm, Oluf Pedersen, Allan Linneberg, Bolette Hartmann, Jens Juul Holst, Torben Hansen, Shane C Wright, Volker Martin Lauschke, Niels Grarup, Alexander Sebastian Hauser, Mette Marie Rosenkilde
Characterization of genetic variants of GIPR reveals a contribution of β-arrestin to metabolic phenotypes. Nature metabolism 6 (7) (2024)
Christian Sommerauer, Carlos J Gallardo-Dodd, Christina Savva, Linnea Hases, Madeleine Birgersson, Rajitha Indukuri, Joanne X Shen, Pablo Carravilla, Keyi Geng, Jonas Nørskov Søndergaard, Clàudia Ferrer-Aumatell, Grégoire Mercier, Erdinc Sezgin, Marion Korach-André, Carl Petersson, Hannes Hagström, Volker Martin Lauschke, Amena Archer, Cecilia Williams, Claudia Kutter
Estrogen receptor activation remodels TEAD1 gene expression to alleviate hepatic steatosis. Molecular systems biology 20 (4) (2024)
Hüsün S Kizilkaya, Kimmie V Sørensen, Jakob Sture Madsen, Peter Lindquist, Jonathan D Douros, Jette Bork-Jensen, Alessandro Berghella, Peter A Gerlach, Laerke Smidt Gasbjerg, Jacek Mokrosinski, Stephanie A Mowery, Patrick J Knerr, Brian Finan, Jonathan E Campbell, David A D'Alessio, Diego Perez-Tilve, Felix Faas, Signe Mathiasen, Jørgen Rungby, Henrik Toft Sorensen, Allan Vaag, Jens Steen Nielsen, Jens-Christian Holm, Jeannet Lauenborg, Nis Peter Damm, Oluf Pedersen, Allan Linneberg, Bolette Hartmann, Jens Juul Holst, Torben Hansen, Shane C Wright, Volker Martin Lauschke, Niels Grarup, Alexander Sebastian Hauser, Mette Marie Rosenkilde
Characterization of genetic variants of GIPR reveals a contribution of β-arrestin to metabolic phenotypes. Nature metabolism 6 (7) (2024)
Hüsün S Kizilkaya, Kimmie V Sørensen, Jakob Sture Madsen, Peter Lindquist, Jonathan D Douros, Jette Bork-Jensen, Alessandro Berghella, Peter A Gerlach, Laerke Smidt Gasbjerg, Jacek Mokrosinski, Stephanie A Mowery, Patrick J Knerr, Brian Finan, Jonathan E Campbell, David A D'Alessio, Diego Perez-Tilve, Felix Faas, Signe Mathiasen, Jørgen Rungby, Henrik Toft Sorensen, Allan Vaag, Jens Steen Nielsen, Jens-Christian Holm, Jeannet Lauenborg, Nis Peter Damm, Oluf Pedersen, Allan Linneberg, Bolette Hartmann, Jens Juul Holst, Torben Hansen, Shane C Wright, Volker Martin Lauschke, Niels Grarup, Alexander Sebastian Hauser, Mette Marie Rosenkilde
Characterization of genetic variants of GIPR reveals a contribution of β-arrestin to metabolic phenotypes. Nature metabolism 6 (7) (2024)
Yitian Zhou, Volker Martin Lauschke
Next-generation sequencing in pharmacogenomics - fit for clinical decision support? Expert review of clinical pharmacology (2024)
Yitian Zhou, Sebastian Pirmann, Volker Martin Lauschke
APF2: an improved ensemble method for pharmacogenomic variant effect prediction. The pharmacogenomics journal 24 (3) (2024)
Yitian Zhou, Volker Martin Lauschke
Next-generation sequencing in pharmacogenomics - fit for clinical decision support? Expert review of clinical pharmacology 17 (3) (2024)
Hüsün S Kizilkaya, Kimmie V Sørensen, Jakob Sture Madsen, Peter Lindquist, Jonathan D Douros, Jette Bork-Jensen, Alessandro Berghella, Peter A Gerlach, Laerke Smidt Gasbjerg, Jacek Mokrosinski, Stephanie A Mowery, Patrick J Knerr, Brian Finan, Jonathan E Campbell, David A D'Alessio, Diego Perez-Tilve, Felix Faas, Signe Mathiasen, Jørgen Rungby, Henrik Toft Sorensen, Allan Vaag, Jens Steen Nielsen, Jens-Christian Holm, Jeannet Lauenborg, Nis Peter Damm, Oluf Pedersen, Allan Linneberg, Bolette Hartmann, Jens Juul Holst, Torben Hansen, Shane C Wright, Volker Martin Lauschke, Niels Grarup, Alexander Sebastian Hauser, Mette Marie Rosenkilde
Characterization of genetic variants of GIPR reveals a contribution of β-arrestin to metabolic phenotypes. Nature metabolism 6 (7) (2024)
Mahamadou D Camara, Yitian Zhou, Antoine Dara, Mamadou M Tékété, Taís Nóbrega de Sousa, Sékou Sissoko, Laurent Dembele, Nouhoun Ouologuem, Amadou Hamidou Togo, Mohamed L Alhousseini, Bakary Fofana, Issaka Sagara, Abdoulaye A Djimde, Pedro J Gil, Volker Martin Lauschke
Population-specific variations in KCNH2 predispose patients to delayed ventricular repolarization upon dihydroartemisinin-piperaquine therapy. Antimicrobial agents and chemotherapy (2024)
Vanessa M Monteil, Shane C Wright, Matheus Dyczynski, Max J Kellner, Sofia K Appelberg, Sebastian Wolfgang Platzer, Ahmed Ibrahim, Hyesoo Kwon, Ioannis Pittarokoilis, Mattia Mirandola, Georg Michlits, Stéphanie Devignot, Elizabeth G Elder, Samir Abdurahman, Sándor Bereczky, Binnur Bagci, Sonia Youhanna, Teodor Aastrup, Volker Martin Lauschke, Cristiano Salata, Nazif Elaldi, Friedemann Weber, Nuria Montserrat, David W Hawman, Heinrich Feldmann, Moritz Horn, Josef M Penninger, Ali Mirazimi
Crimean-Congo haemorrhagic fever virus uses LDLR to bind and enter host cells. Nature microbiology 9 (6) (2024)
Christian Sommerauer, Carlos J Gallardo-Dodd, Christina Savva, Linnea Hases, Madeleine Birgersson, Rajitha Indukuri, Joanne X Shen, Pablo Carravilla, Keyi Geng, Jonas Nørskov Søndergaard, Clàudia Ferrer-Aumatell, Grégoire Mercier, Erdinc Sezgin, Marion Korach-André, Carl Petersson, Hannes Hagström, Volker Martin Lauschke, Amena Archer, Cecilia Williams, Claudia Kutter
Estrogen receptor activation remodels TEAD1 gene expression to alleviate hepatic steatosis. Molecular systems biology 20 (4) (2024)
Stefania Koutsilieri, Evgeniya Mickols, Ákos Végvári, Volker Martin Lauschke
Proteomic workflows for deep phenotypic profiling of 3D organotypic liver models. Biotechnology journal 19 (3) (2024)
Shane C Wright, Aikaterini Motso, Stefania Koutsilieri, Christian Michel Beusch, Pierre Sabatier, Alessandro Berghella, Élodie Blondel-Tepaz, Kimberley Mangenot, Ioannis Pittarokoilis, Despoina-Christina Sismanoglou, Christian Le Gouill, Jesper Velgaard Olsen, Roman A Zubarev, Nevin A Lambert, Alexander Sebastian Hauser, Michel Bouvier, Volker Martin Lauschke
GLP-1R signaling neighborhoods associate with the susceptibility to adverse drug reactions of incretin mimetics. Nature communications 14 (1) (2023)
Chiea Chuen Khor, Stefan Winter, Natalia Sutiman, Thomas E Mürdter, Sylvia Chen, Joanne Siok Liu Lim, Zheng Li, Jingmei Li, Kar-Seng Sim, Boian Ganchev, Diana Eccles, Bryony Eccles, William Tapper, Nathalie Khoueiry Zgheib, Arafat Tfayli, Raymond Chee Hui Ng, Yoon Sim Yap, Elaine Lim, Mabel Wong, Nan Soon Wong, Peter Cher Siang Ang, Rebecca Dent, Roman Tremmel, Kathrin Klein, Elke Schaeffeler, Yitian Zhou, Volker Martin Lauschke, Michel Eichelbaum, Matthias Schwab, Hiltrud B Brauch, Balram Chowbay, Werner Schroth
Cross-Ancestry Genome-Wide Association Study Defines the Extended CYP2D6 Locus as the Principal Genetic Determinant of Endoxifen Plasma Concentrations. Clinical pharmacology and therapeutics 113 (3) (2023)
Shane C Wright, Volker Martin Lauschke
Rewiring of catecholamine-induced calcium signaling is an early event in non-alcoholic fatty liver disease. The Journal of physiology (2023)
Chiea Chuen Khor, Stefan Winter, Natalia Sutiman, Thomas E Mürdter, Sylvia Chen, Joanne Siok Liu Lim, Zheng Li, Jingmei Li, Kar-Seng Sim, Boian Ganchev, Diana Eccles, Bryony Eccles, William Tapper, Nathalie Khoueiry Zgheib, Arafat Tfayli, Raymond Chee Hui Ng, Yoon Sim Yap, Elaine Lim, Mabel Wong, Nan Soon Wong, Peter Cher Siang Ang, Rebecca Dent, Roman Tremmel, Kathrin Klein, Elke Schaeffeler, Yitian Zhou, Volker Martin Lauschke, Michel Eichelbaum, Matthias Schwab, Hiltrud B Brauch, Balram Chowbay, Werner Schroth
Cross-Ancestry Genome-Wide Association Study Defines the Extended CYP2D6 Locus as the Principal Genetic Determinant of Endoxifen Plasma Concentrations. Clinical pharmacology and therapeutics 113 (3) (2023)
Lipeng Ren, Jérémie Charbord, Lianhe Chu, Aurino M Kemas, Maria Bertuzzi, Jiarui Mi, Chen Xing, Volker Martin Lauschke, Olov Andersson
Adjudin improves beta cell maturation, hepatic glucose uptake and glucose homeostasis. Diabetologia (2023)
Chiea Chuen Khor, Stefan Winter, Natalia Sutiman, Thomas E Mürdter, Sylvia Chen, Joanne Siok Liu Lim, Zheng Li, Jingmei Li, Kar-Seng Sim, Boian Ganchev, Diana Eccles, Bryony Eccles, William Tapper, Nathalie Khoueiry Zgheib, Arafat Tfayli, Raymond Chee Hui Ng, Yoon Sim Yap, Elaine Lim, Mabel Wong, Nan Soon Wong, Peter Cher Siang Ang, Rebecca Dent, Roman Tremmel, Kathrin Klein, Elke Schaeffeler, Yitian Zhou, Volker Martin Lauschke, Michel Eichelbaum, Matthias Schwab, Hiltrud B Brauch, Balram Chowbay, Werner Schroth
Cross-Ancestry Genome-Wide Association Study Defines the Extended CYP2D6 Locus as the Principal Genetic Determinant of Endoxifen Plasma Concentrations. Clinical pharmacology and therapeutics 113 (3) (2023)
Vanessa M Monteil, Hyesoo Kwon, Lijo John, Cristiano Salata, Gustav Jonsson, Sabine U Vorrink, Sofia K Appelberg, Sonia Youhanna, Matheus Dyczynski, Alexandra Leopoldi, Nicole Leeb, Jennifer Volz, Astrid Hagelkruys, Max J Kellner, Stéphanie Devignot, Georg Michlits, Michelle Foong-Sobis, Friedemann Weber, Volker Martin Lauschke, Moritz Horn, Heinrich Feldmann, Ulrich Elling, Josef M Penninger, Ali Mirazimi
Identification of CCZ1 as an essential lysosomal trafficking regulator in Marburg and Ebola virus infections. Nature communications 14 (1) (2023)
Chiea Chuen Khor, Stefan Winter, Natalia Sutiman, Thomas E Mürdter, Sylvia Chen, Joanne Siok Liu Lim, Zheng Li, Jingmei Li, Kar-Seng Sim, Boian Ganchev, Diana Eccles, Bryony Eccles, William Tapper, Nathalie Khoueiry Zgheib, Arafat Tfayli, Raymond Chee Hui Ng, Yoon Sim Yap, Elaine Lim, Mabel Wong, Nan Soon Wong, Peter Cher Siang Ang, Rebecca Dent, Roman Tremmel, Kathrin Klein, Elke Schaeffeler, Yitian Zhou, Volker Martin Lauschke, Michel Eichelbaum, Matthias Schwab, Hiltrud B Brauch, Balram Chowbay, Werner Schroth
Cross-Ancestry Genome-Wide Association Study Defines the Extended CYP2D6 Locus as the Principal Genetic Determinant of Endoxifen Plasma Concentrations. Clinical pharmacology and therapeutics (2023)
Chiea Chuen Khor, Stefan Winter, Natalia Sutiman, Thomas E Mürdter, Sylvia Chen, Joanne Siok Liu Lim, Zheng Li, Jingmei Li, Kar-Seng Sim, Boian Ganchev, Diana Eccles, Bryony Eccles, William Tapper, Nathalie Khoueiry Zgheib, Arafat Tfayli, Raymond Chee Hui Ng, Yoon Sim Yap, Elaine Lim, Mabel Wong, Nan Soon Wong, Peter Cher Siang Ang, Rebecca Dent, Roman Tremmel, Kathrin Klein, Elke Schaeffeler, Yitian Zhou, Volker Martin Lauschke, Michel Eichelbaum, Matthias Schwab, Hiltrud B Brauch, Balram Chowbay, Werner Schroth
Cross-Ancestry Genome-Wide Association Study Defines the Extended CYP2D6 Locus as the Principal Genetic Determinant of Endoxifen Plasma Concentrations. Clinical pharmacology and therapeutics 113 (3) (2023)
Roman Tremmel, Yitian Zhou, Matthias Schwab, Volker Martin Lauschke
Structural variation of the coding and non-coding human pharmacogenome. NPJ genomic medicine 8 (1) (2023)
Gisela Nilsson, Amin Mottahedin, Aura Zelco, Volker Martin Lauschke, C Joakim Ek, Juan Song, Maryam Ardalan, Sha Hua, Xiaoli Zhang, Carina Mallard, Henrik Hagberg, Jianmei Wu Leavenworth, Xiaoyang Wang
Two different isoforms of osteopontin modulate myelination and axonal integrity. FASEB bioAdvances 5 (8) (2023)
Emelie Barreby, Benedikt Strunz, Sebastian Nock, Léa Naudet, Joanne X Shen, Helene Johansson, Isabella Sönnerborg, Junjie Ma, Egon Urgard, Laura J Pallett, Yizhou Hu, Achilleas Fardellas, Valerio Azzimato, Ana Vankova, Laura Levi, Cecilia Morgantini, Mala K Maini, Per Stål, Stephan P Rosshart, Jonathan M Coquet, Greg Nowak, Näslund Erik, Volker Martin Lauschke, Ewa C S Ellis, Niklas K Björkström, Ping Chen, Myriam Aouadi
Human resident liver myeloid cells protect against metabolic stress in obesity. Nature metabolism (2023)
Martin Novak, Marie Vajrychova, Stefania Koutsilieri, Despoina-Christina Sismanoglou, Tereza Kobrlova, Lukas Prchal, Barbora Svobodova, Jan Korabecny, Tomas Zarybnicky, Lucie Raisova-Stuchlikova, Lenka Skalova, Volker Martin Lauschke, Radim Kučera, Ondrej Soukup
Tacrine First-Phase Biotransformation and Associated Hepatotoxicity: A Possible Way to Avoid Quinone Methide Formation. ACS chemical biology (2023)
Chiea Chuen Khor, Stefan Winter, Natalia Sutiman, Thomas E Mürdter, Sylvia Chen, Joanne Siok Liu Lim, Zheng Li, Jingmei Li, Kar-Seng Sim, Boian Ganchev, Diana Eccles, Bryony Eccles, William Tapper, Nathalie Khoueiry Zgheib, Arafat Tfayli, Raymond Chee Hui Ng, Yoon Sim Yap, Elaine Lim, Mabel Wong, Nan Soon Wong, Peter Cher Siang Ang, Rebecca Dent, Roman Tremmel, Kathrin Klein, Elke Schaeffeler, Yitian Zhou, Volker Martin Lauschke, Michel Eichelbaum, Matthias Schwab, Hiltrud B Brauch, Balram Chowbay, Werner Schroth
Cross-Ancestry Genome-Wide Association Study Defines the Extended CYP2D6 Locus as the Principal Genetic Determinant of Endoxifen Plasma Concentrations. Clinical pharmacology and therapeutics 113 (3) (2023)
Yoomi Park, Volker Martin Lauschke
Towards more accurate pharmacogenomic variant effect predictions. Pharmacogenomics (2023)
Claudia Tredup, Benardina Ndreshkjana, Natalie S Schneider, Amelie Tjaden, Aurino M Kemas, Sonia Youhanna, Volker Martin Lauschke, Benedict-Tilmann Berger, Andreas Krämer, Lena Marie Berger, Sandra Röhm, Stefan Knapp, Henner F Farin, Susanne Müller
Deep Annotation of Donated Chemical Probes (DCP) in Organotypic Human Liver Cultures and Patient-Derived Organoids from Tumor and Normal Colorectum. ACS chemical biology (2023)
Roman Tremmel, Sebastian Pirmann, Yitian Zhou, Volker Martin Lauschke
Translating pharmacogenomic sequencing data into drug response predictions - how to interpret variants of unknown significance. British journal of clinical pharmacology (2023)
Aurino M Kemas, Reza Zandi Shafagh, Nayere Taebnia, Maurice Michel, Lena Preiss, Ute Hofmann, Volker Martin Lauschke
Compound Absorption in Polymer Devices Impairs The Translatability of Preclinical Safety Assessments. Advanced healthcare materials (2023)
Shane C Wright, Volker Martin Lauschke
Rewiring of catecholamine-induced calcium signalling is an early event in non-alcoholic fatty liver disease. The Journal of physiology (2023)
Carolina Dagli Hernandez, Jessica Bassani Borges, Elisangela da Silva Rodrigues Marçal, Renata Caroline Costa de Freitas, Augusto Akira Mori, Rodrigo Marques Gonçalves, Andre Arpad Faludi, Victor Fernandes de Oliveira, Glaucio Monteiro Ferreira, Gisele Medeiros Bastos, Yitian Zhou, Volker Martin Lauschke, Álvaro Cerda, Mario Hiroyuki Hirata, Rosario Dominguez Crespo Hirata
Genetic Variant ABCC1 rs45511401 Is Associated with Increased Response to Statins in Patients with Familial Hypercholesterolemia. Pharmaceutics 14 (5) (2022)
Yitian Zhou, Stefania Koutsilieri, Erik Eliasson, Volker Martin Lauschke
A paradigm shift in pharmacogenomics: From candidate polymorphisms to comprehensive sequencing. Basic & clinical pharmacology & toxicology 131 (6) (2022)
Nayere Taebnia, Ute Römling, Volker Martin Lauschke
In vitro and ex vivo modeling of enteric bacterial infections. Gut microbes 15 (1) (2022)
Qingyang Xiao, Stefania Koutsilieri, Despoina-Christina Sismanoglou, Volker Martin Lauschke
CFTR reduces the proliferation of lung adenocarcinoma and is a strong predictor of survival in both smokers and non-smokers. Journal of cancer research and clinical oncology 148 (12) (2022)
Nayere Taebnia, Ute Römling, Volker Martin Lauschke
In vitro and ex vivo modeling of enteric bacterial infections. Gut microbes 15 (1) (2022)
Yitian Zhou, Volker Martin Lauschke
The genetic landscape of major drug metabolizing cytochrome P450 genes-an updated analysis of population-scale sequencing data. The pharmacogenomics journal 22 (5-6) (2022)
Hristo Y Ivanov, Denitsa Grigorova, Volker Martin Lauschke, Branimir Velinov, Kaloyan Stoychev, Gergana Kyosovska, Peter Shopov
CYP2C19 and CYP2D6 Genotypes and Metabolizer Status Distribution in a Bulgarian Psychiatric Cohort. Journal of personalized medicine 12 (7) (2022)
Nayere Taebnia, Ute Römling, Volker Martin Lauschke
In vitro and ex vivo modeling of enteric bacterial infections. Gut microbes 15 (1) (2022)
Nayere Taebnia, Ute Römling, Volker Martin Lauschke
In vitro and ex vivo modeling of enteric bacterial infections. Gut microbes 15 (1) (2022)
Reza Zandi Shafagh, Sonia Youhanna, Jibbe Keulen, Joanne X Shen, Nayere Taebnia, Lena C Preiss, Kathrin Klein, Florian A Büttner, Mikael Bergqvist, Wouter van der Wijngaart, Volker Martin Lauschke
Bioengineered Pancreas-Liver Crosstalk in a Microfluidic Coculture Chip Identifies Human Metabolic Response Signatures in Prediabetic Hyperglycemia. Advanced science (Weinheim, Baden-Wurttemberg, Germany) (2022)
Magnus Ingelman-Sundberg, Volker Martin Lauschke
3D human liver spheroids for translational pharmacology and toxicology. Basic & clinical pharmacology & toxicology (2021)
Joanne X Shen, Morgane Couchet, Jérémy Dufau, Thais de Castro Barbosa, Maximilian H Ulbrich, Martin Helmstädter, Aurino M Kemas, Reza Zandi Shafagh, Marie-Adeline Marques, Jacob B Hansen, Niklas Mejhert, Dominique Langin, Mikael Rydén, Volker Martin Lauschke
3D Adipose Tissue Culture Links the Organotypic Microenvironment to Improved Adipogenesis. Advanced science (Weinheim, Baden-Wurttemberg, Germany) 8 (16) (2021)
Justin Stebbing, Ginés Sánchez Nievas, Marco Falcone, Sonia Youhanna, Peter Richardson, Silvia Ottaviani, Joanne X Shen, Christian Sommerauer, Giusy Tiseo, Lorenzo Ghiadoni, Agostino Virdis, Fabio Monzani, Luis Romero Rizos, Francesco Forfori, Almudena Avendaño Céspedes, Salvatore De Marco, Laura Carrozzi, Fabio Lena, Pedro Manuel Sánchez-Jurado, Leonardo Gianluca Lacerenza, Nencioni Cesira, David Caldevilla Bernardo, Antonio Perrella, Laura Niccoli, Lourdes Sáez Méndez, Daniela Matarrese, Delia Goletti, Yee Joo Tan, Vanessa M Monteil, George Dranitsaris, Fabrizio Cantini, Alessio Farcomeni, Shuchismita Dutta, Stephen K Burley, Mirjana Jerkic, Mauro Pistello, William Li, Marta Mas Romero, Fernando Andrés Pretel, Rafaela Sánchez Simón-Talero, Rafael García-Molina, Claudia Kutter, James H Felce, Zehra F Nizami, Andras G Miklosi, Josef M Penninger, Francesco Menichetti, Ali Mirazimi, Pedro Abizanda Soler, Volker Martin Lauschke
JAK inhibition reduces SARS-CoV-2 liver infectivity and modulates inflammatory responses to reduce morbidity and mortality. Science advances 7 (1) (2021)
Qingyang Xiao, Volker Martin Lauschke
The prevalence, genetic complexity and population-specific founder effects of human autosomal recessive disorders. NPJ genomic medicine 6 (1) (2021)
Valerio Azzimato, Jennifer Jager, Ping Chen, Cecilia Morgantini, Laura Levi, Emelie Barreby, André Sulen, Carolina Oses, Joost Willerbrords, Connie Xu, Xidan Li, Joanne X Shen, Naveed Akbar, Lars Haag, Ewa C S Ellis, Kerstin Wålhen, Näslund Erik, Anders Thorell, Robin P Choudhury, Volker Martin Lauschke, Mikael Rydén, Siobhan M Craige, Myriam Aouadi
Liver macrophages inhibit the endogenous antioxidant response in obesity-associated insulin resistance. Science translational medicine 12 (532) (2021)
Yitian Zhou, Volker Martin Lauschke
Population pharmacogenomics: an update on ethnogeographic differences and opportunities for precision public health. Human genetics (2021)
Aurino M Kemas, Sonia Youhanna, Reza Zandi Shafagh, Volker Martin Lauschke
Insulin-dependent glucose consumption dynamics in 3D primary human liver cultures measured by a sensitive and specific glucose sensor with nanoliter input volume. FASEB journal : official publication of the Federation of American Societies for Experimental Biology 35 (3) (2021)
Yitian Zhou, Gabriel Herras Arribas, Ainoleena Turku, Tuuli Jürgenson, Souren Mkrtchian, Kristi Krebs, Yi Wang, Barbora Svobodova, Lili A Milani, Gunnar Schulte, Jan Korabecny, Stefano Gastaldello, Volker Martin Lauschke
Rare genetic variability in human drug target genes modulates drug response and can guide precision medicine. Science advances 7 (36) (2021)
Thiago Dominguez Crespo Hirata, Carolina Dagli Hernandez, Fabiana Dalla Vecchia Genvigir, Volker Martin Lauschke, Yitian Zhou, Mario Hiroyuki Hirata, Rosario Dominguez Crespo Hirata
Cardiovascular Pharmacogenomics: An Update on Clinical Studies of Antithrombotic Drugs in Brazilian Patients. Molecular diagnosis & therapy 25 (6) (2021)
Vanessa M Monteil, Matheus Dyczynski, Volker Martin Lauschke, Hyesoo Kwon, Gerald Wirnsberger, Sonia Youhanna, Mirjana Jerkic, Arthur S Slutsky, Carmen Hurtado Del Pozo, Moritz Horn, Nuria Montserrat, Josef M Penninger, Ali Mirazimi
Human soluble ACE2 improves the effect of remdesivir in SARS-CoV-2 infection. EMBO molecular medicine 13 (1) (2020)
Nuria Oliva-Vilarnau, Sabine U Vorrink, Magnus Ingelman-Sundberg, Volker Martin Lauschke
A 3D Cell Culture Model Identifies Wnt/β-Catenin Mediated Inhibition of p53 as a Critical Step during Human Hepatocyte Regeneration. Advanced science (Weinheim, Baden-Wurttemberg, Germany) 7 (15) (2020)
Volker Martin Lauschke, Åsa Nordling, Yitian Zhou, Sara Fontalva, Isabel Barragan, Magnus Ingelman-Sundberg
CYP3A5 is unlikely to mediate anticancer drug resistance in hepatocellular carcinoma. Pharmacogenomics 20 (15) (2020)
Qingyang Xiao, Yitian Zhou, Volker Martin Lauschke
Impact of variants in ATP-binding cassette transporters on breast cancer treatment. Pharmacogenomics 21 (18) (2020)
Laura E Russell, Yitian Zhou, Volker Martin Lauschke, Richard B Kim
In Vitro Functional Characterization and in Silico Prediction of Rare Genetic Variation in the Bile Acid and Drug Transporter, Na+-Taurocholate Cotransporting Polypeptide (NTCP, SLC10A1). Molecular pharmaceutics 17 (4) (2020)
Fotios Kounelis, Alexandros Kanterakis, Andreas Kanavos, Maria-Theodora Pandi, Zoe Kordou, Olivia Manusama, Gerasimos Vonitsanos, Theodora Katsila, Evangelia-Eirini Tsermpini, Volker Martin Lauschke, Maria Koromina, Peter J van der Spek, George P Patrinos
Documentation of clinically relevant genomic biomarker allele frequencies in the next-generation FINDbase worldwide database. Human mutation 41 (6) (2020)
Qingyang Xiao, André Nobre, Pilar Piñeiro, Miguel-Ángel Berciano-Guerrero, Emilio Alba, Manuel Cobo, Volker Martin Lauschke, Isabel Barragán
Genetic and Epigenetic Biomarkers of Immune Checkpoint Blockade Response. Journal of clinical medicine 9 (1) (2020)
Reza Zandi Shafagh, Joanne X Shen, Sonia Youhanna, Weijin Guo, Volker Martin Lauschke, Wouter van der Wijngaart, Tommy Haraldsson
Facile Nanoimprinting of Robust High-Aspect-Ratio Nanostructures for Human Cell Biomechanics. ACS applied bio materials 3 (12) (2020)
Qingyang Xiao, Yitian Zhou, Stefan Winter, Florian Büttner, Elke Schaeffeler, Matthias Schwab, Volker Martin Lauschke
Germline variant burden in multidrug resistance transporters is a therapy-specific predictor of survival in breast cancer patients. International journal of cancer 146 (9) (2020)
Volker Martin Lauschke, Magnus Ingelman-Sundberg
Emerging strategies to bridge the gap between pharmacogenomic research and its clinical implementation. NPJ genomic medicine 5 (2020)
Yitian Zhou, Carolina Dagli Hernandez, Volker Martin Lauschke
Population-scale predictions of DPD and TPMT phenotypes using a quantitative pharmacogene-specific ensemble classifier. British journal of cancer 123 (12) (2020)
Qingyang Xiao, Yitian Zhou, Volker Martin Lauschke
Ethnogeographic and inter-individual variability of human ABC transporters. Human genetics 139 (5) (2020)
Cathelijne H van der Wouden, Mandy H van Rhenen, Wafa O M Jama, Magnus Ingelman-Sundberg, Volker Martin Lauschke, Lidija Konta, Matthias Schwab, Jesse Joachim Swen, Henk-Jan Guchelaar
Development of the PGx-Passport: A Panel of Actionable Germline Genetic Variants for Pre-Emptive Pharmacogenetic Testing. Clinical pharmacology and therapeutics 106 (4) (2019)

Volker Martin Lauschke.css-eqlu8i{font-size:small;padding-left:4px;} (Volker Lauschke, Volker M Lauschke, Volker M Lauschke)

Publication Activity (10 Years)

Top Topics

Top Venues

Volker Martin Lauschke (Volker Lauschke, Volker M Lauschke, Volker M Lauschke)