Gross type of hepatocellular carcinoma reflects the tumor hypoxia, fibrosis, and stemness-related marker expression.

Hyungjin RheeTaek ChungJeong Eun YooJi Hae NahmHa Young WooGi Hong ChoiDai Hoon HanYoung Nyun Park

Published in: Hepatology international (2020)

The marker expression of stemness-related and hypoxic/fibrotic TME of HCC showed an increasing trend in order of VN-SN-SNEG-CM-INF gross types, and their cross-talk may be involved in the determination of various gross-morphological features and their distinct biological behavior.

Keyphrases

poor prognosis
stem cells
children with cerebral palsy
epithelial mesenchymal transition
binding protein
systemic sclerosis
endothelial cells
long non coding rna
idiopathic pulmonary fibrosis
cancer stem cells
high resolution
drug induced
liver fibrosis