Bempedoic Acid and Ezetimibe for the Treatment of Hypercholesterolemia: A Systematic Review and Meta-Analysis of Randomized Phase II/III trials.

Akshaya Srikanth BhagavathulaNadya Obaid Al MatrooshiCain C T ClarkJamal Rahmani

Published in: Clinical drug investigation (2020)

This review found bempedoic acid and ezetimibe significantly lowered lipid parameters, attenuated hsCRP levels, and had an acceptable safety profile for the treatment of hypercholesterolemia and ASCVD.

Keyphrases

phase ii
open label
clinical trial
double blind
phase iii
placebo controlled
cardiovascular events
type diabetes
combination therapy
fatty acid