Landmark Cancer Clinical Trials and Real-World Patient Populations: Examining Race and Age Reporting.
Thejus T JayakrishnanSonikpreet AulakhMizba BakshKianna NguyenMeghna AilawadhiAyesha SamreenRicardo ParrondoTaimur SherVivek RoyRami ManochakianAneel PaulusAsher Chanan-KhanSikander AilawadhiPublished in: Cancers (2021)
The study demonstrates that a significant number of clinical trials leading to cancer drug approvals suffer from racial and age disparity when compared to real-world populations, and that the two factors may be interrelated. We recommend continued efforts to recruit diverse populations.