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Landmark Cancer Clinical Trials and Real-World Patient Populations: Examining Race and Age Reporting.

Thejus T JayakrishnanSonikpreet AulakhMizba BakshKianna NguyenMeghna AilawadhiAyesha SamreenRicardo ParrondoTaimur SherVivek RoyRami ManochakianAneel PaulusAsher Chanan-KhanSikander Ailawadhi
Published in: Cancers (2021)
The study demonstrates that a significant number of clinical trials leading to cancer drug approvals suffer from racial and age disparity when compared to real-world populations, and that the two factors may be interrelated. We recommend continued efforts to recruit diverse populations.
Keyphrases
  • clinical trial
  • papillary thyroid
  • adverse drug
  • randomized controlled trial
  • phase ii
  • emergency department
  • lymph node metastasis
  • childhood cancer
  • african american
  • study protocol
  • open label