A Prospective Study of Cyclosporine A 0.1% Combined with Loteprednol 0.2% vs Cyclosporine A 0.05% Alone in the Treatment of Dry Eye.

John A Hovanesian Thomas ChesterRobert C Sorenson

Published in: Clinical ophthalmology (Auckland, N.Z.) (2023)

The combination of CsA 0.1%-LE 0.2% provided significant improvement in corneal HOAs, while CsA 0.05% did not. For all other measures of ocular surface improvement, both medications showed similar benefits. Tolerability was comparable between the formulations. When rapid rehabilitation of the ocular surface is needed to reduce aberrations, CsA-LE is an appropriate choice.

Keyphrases

copy number
optical coherence tomography
randomized controlled trial
dna methylation
gene expression
wound healing
double blind
decision making
replacement therapy
placebo controlled