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Immunosuppression Considerations for Older Kidney Transplant Recipients.

Wisit CheungpasitpornKrista L LentineJane C TanMatthew KaufmannYasar CaliskanSuphamai BunnapradistNgan N LamMark SchnitzlerDavid A Axelrod
Published in: Current transplantation reports (2021)
Tailored immunosuppression management to improve patient and graft survival in older transplant recipients is an important goal of personalized medicine. Lower intensity immunosuppression, such as steroid-sparing regimens, appear beneficial whereas mTORi- and cyclosporine-based maintenance are associated with greater potential for adverse effects. Prospective clinical trials to assess the safety and efficacy of immunosuppression agents in older recipients are urgently needed.
Keyphrases
  • community dwelling
  • clinical trial
  • middle aged
  • physical activity
  • randomized controlled trial
  • high intensity
  • smoking cessation
  • robot assisted
  • placebo controlled